Involvement of microglial CD40 in murine retrovirus-induced peripheral neuropathy
نویسندگان
چکیده
منابع مشابه
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LP-BM5 retrovirus-infected C57BL/6 mice develop splenomegaly, lymphadenopathy, hypergammaglobulinemia, and immunodeficiency; thus, this disease has been named mouse AIDS. In this syndrome, CD154/CD40 interactions are required for but do not mediate disease by upregulation of CD80 or CD86. We report here that there is nonetheless a necessity for CD40 signaling competence, specifically an intact ...
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ژورنال
عنوان ژورنال: Journal of Neuroimmunology
سال: 2013
ISSN: 0165-5728
DOI: 10.1016/j.jneuroim.2013.04.023